[23] Antivitamin B 12 compounds (often synthetic B 12 analogues) not only have no vitamin action, but also actively interfere with the activity of true vitamin B 12
GLP-1R, widely distributed in the central nervous system, plays a crucial role in regulating various brain pathological processes, including neuroinflammation, nutrient metabolism, mitochondrial function, and synaptic function [50,51,52]
Macrophage activation and foam cell formation may explain the elevated CRP serum levels and contribute to disease progression (Figure 3)
Nootropic drugs are legal but require a prescription
Korkushko OV, Khavinson VKh, Shatilo VB, Antonyuk-Shcheglova IA
Hits were pre-screened for potential liabilities based on known reactive properties of small molecules using the FILTER tool before running the structure-based screening